June 30, 2020 – Novozymes today announced the launch of a unique and advanced enzyme solution for cleaning surgical instruments and devices – Remify Everis 100 L*. Preventing Healthcare Associated Infections (HAIs) has become more important than ever also with the COVID-19 pandemic. Not only can these result in death, but also in significant costs and loss of reputation for hospitals. It is well-recognized by the industry that inadequately cleaned surgical equipment is a key source of HAIs.

"The current cleaning processes used for medical devices, including multiuse endoscopes and surgical instruments, do not always guarantee that instruments are free of contamination. The formulation of the detergent used is crucial in effectiveness,” says Rene Garza, Novozymes’ Vice President for Household Care Americas. “Remify Everis 100 L is a unique and patented phosphodiesterase (PDE) – a nuclease – that removes free DNA soils. It has never been possible to specifically target these with detergent ingredients before.” 

Remify Everis 100 L represents a brand-new enzyme class for detergents that can be used to help prevent HAIs. The technology is only available from Novozymes and is the first as part of a new product portfolio for medical device cleaning that the company will launch later this year. 


Proven performance 

Novozymes has invested significantly in research into the performance of its new technology and the results have shown that detergents, optimized by using Remify Everis 100 L, one of the company’s most advanced enzymes, provide better cleaning performance at the right dosages, removing stuck-on soils quicker and with less effort. 

"With appropriate use of Remify Everis 100 L, healthcare organizations can improve patient outcomes by reducing the risk of HAIs. Other benefits are improved rewash rates and decreased operational costs,” adds Rene Garza.

With demand for effective hygiene products at an all-time high, the launch of Novozymes’ Remify Everis 100 L provides detergent manufacturers with a new option to satisfy customer requirements. Novozymes anticipates that the product will play a significant role in medical device cleaning in the future.  

More information on Remify Everis 100 L can be found here.


   An advanced enzyme that offers superior performance:

  • Remify Everis 100 L is an enzyme or biomolecules that speeds up reactions and can specifically target the organic matter commonly found in medical-type soils. 
  • Enzymes are gentle on delicate medical instruments and devices. They are readily biodegradable.
  • Enzyme function can be optimized to ensure proper cleaning by monitoring key factors such as temperature, dose, and time.
  • The two most used enzymes used to clean medical devices today are protease and lipase. 
  • Proteases are designed to break down protein-rich soils like blood, while lipases target fatty soils like adipose tissue. Other enzymes traditionally used in this application are amylases and cellulases, which break down starch and cellulosic polymers respectively, to facilitate their removal. These target soils may be found in human waste, such as feces. 
  • Combining multiple enzymes with a properly formulated detergent can help break down a variety of human soils and waste. 

* Please note this product was renamed to Everis™ Next.

Novozymes Contact:

Frederik Bjoerndal | Corporate Press Manager, Global | +1-646-671-3897 | TFBH@novozymes.com