Sustine® 120 IM is a 1,3 immobilized lipase that offers recyclability and works well with stereoselective hydrolysis and desymmetrization of esters.
Sustine® 120 IM can be applied in the manufacturing of commercial active pharmaceutical ingredients (APIs), such as:
As well as intermediates/transformations for:
Metronidazole, nimorazole and benznidazole (by Michael addition)
Sugar-containing coumarins, such as warfarin, armillarisin and novobiocin
Nucleoside analogues of uridine, such as azidothymidine, doxifluridine and telbivudine